MoinMoin
Seems like MoinMoin could be run on a platform like Nexista / Cocoon / Pycoon fairly easily.
action/init.py has an ActionBase class. Use of the "Base" suffix is an interesting idea.
I don't like how MoinMoin mixes logic with presentation.
Misc Basics:
Logging
Errors / exceptions
Debug
How are those functions handled in python?
Review Zope too. Between all the existing Python frameworks it shouldn't be too tough to get a python-powered nexista / cocoon up and running.
Looks like Paste has a javascript console debugger sort of thing, that is a great idea.
I'm not crazy about the mapping of /urls/path/resource to root.urls.path.resource , but maybe it'll grow on me.
Pylons - seems like an MVC / RoR type framework?